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Abdominal Mesothelioma, Mesothelioma, Mesothelioma diagnosis, Mesothelioma Lawyer

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Friday, February 22, 2008

Fwd: Frequent mutations of the CA simple sequence repeat in intron 1 of EGFR in mismatch repair-deficient colorectal cancers.



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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Fri, Feb 22, 2008 at 10:17 AM
Subject: Frequent mutations of the CA simple sequence repeat in intron 1 of EGFR in mismatch repair-deficient colorectal cancers.
To: mesothelioma77@gmail.com


[1]World J Gastroenterol. 2008 Feb 21; 14(7): 1053-9
Buisine MP, Wacrenier A, Mariette C, Leteurtre E, Escande F, Aissi S, Ketele A, Leclercq A, Porchet N, Lesuffleur T

AIM: To investigate the polymorphic simple sequence repeat in intron 1 of the epidermal growth factor receptor gene (EGFR) (CA-SSR I), which is known to affect the efficiency of gene transcription as a putative target of the mismatch repair (MMR) machinery in colorectal tumors. METHODS: The CA-SSR I genotype was analyzed in a total of 86 primary colorectal tumors, selected upon their microsatellite instability (MSI) status [42 with high frequency MSI (MSI-H) and 44 microsatellite stable (MSS)] and their respective normal tissue. The effect of the CA-SSR I genotype on the expression of the EGFR gene was evaluated in 18 specimens using quantitative real-time reverse transcription PCR and immunohistochemistry. RESULTS: Mutations in CA-SSR I were detected in 86% (36 of 42) of MSI-H colorectal tumors and 0% (0 of 44) of MSS tumors, indicating the EGFR gene as a novel putative specific target of the defective MMR system (P

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Source: http://www.hubmed.org/display.cgi?uids=18286687
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Fwd: Multiple gene methylation of nonsmall cell lung cancers evaluated with 3-dimensional microarray.



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From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Fri, Feb 22, 2008 at 10:17 AM
Subject: Multiple gene methylation of nonsmall cell lung cancers evaluated with 3-dimensional microarray.
To: mesothelioma77@gmail.com


[1]Cancer. 2008 Feb 19;
Wang Y, Zhang D, Zheng W, Luo J, Bai Y, Lu Z

BACKGROUND: Aberrant DNA methylation of the CpG islands for cancer-related genes is among the earliest and most frequent alterations in cancer and may be useful for diagnosing cancer or evaluating recurrent disease. METHODS: In this study, a 3-dimensional (3-D), polyacrylamide gel-based DNA microarray coupled with linker-polymerase chain reaction (PCR) was developed to detect hypermethylation of CpG islands in multiple genes from a large group of different samples. The authors determined the frequency of aberrant promoter methylation of 15 genes in 28 resected primary nonsmall cell lung cancers (NSCLCs) and in 12 corresponding nonmalignant lung tissues. RESULTS: Methylation frequencies in the tumor samples were detected in 18% of samples for the breast cancer 1 gene BRCA1, in 43% of samples for the tissue inhibitor of metalloproteinase 3 gene TIMP-3, in 38% of samples for the cyclin-dependent kinase inhibitor 4A gene p16INK4a, in 54% of samples for the cadherin 13 gene CDH13, in 50% of samples for the death-associated protein kinase gene DAPK, in 11% of samples for the E-cadherin gene ECAD, in 25% of samples for the insulin-like growth factor binding protein 7 gene IGFBP7, in 18% of samples for the Ras association domain family 1 gene RASSF1, in 68% of samples for the adenomatous polyposis coli gene APC, in 7% of samples for the cyclin-dependent kinase inhibitor gene p15, in 18% of samples for the CD44 cell adhesion molecule gene, in 29% of samples for the human Mut-L homolog gene hMLH, in 32% of samples for the human telomerase reverse transcriptase gene hTERT, in 64% of samples for the calcitonin gene-related polypeptide alpha gene CALCA, and in 54% of samples for the estrogen receptor gene ER; however, methylation was not observed in the majority of corresponding nonmalignant tissues. Six samples in from 28 tumors had >6 genes methylated, and 1 sample had 13 genes methylated. Methylation of these genes was correlated with some clinicopathologic patient characteristics. CONCLUSIONS: This study demonstrated that a 3-D microarray could be used to detect DNA hypermethylation and provided a high-throughput platform for DNA hypermethylation analysis. Cancer 2008. (c) 2008 American Cancer Society.



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Source: http://www.hubmed.org/display.cgi?uids=18286531
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Fwd: [Systemic treatment of non-small cell lung cancer - recommendations based on the results of reliable clinical trials.]



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From: HubMed - mesothelioma cancer <rssfwd@rssfwd.com>
Date: Fri, Feb 22, 2008 at 10:18 AM
Subject: [Systemic treatment of non-small cell lung cancer - recommendations based on the results of reliable clinical trials.]
To: mesothelioma77@gmail.com


[1]Pneumonol Alergol Pol. 2008; 76(1): 44-52
Jassem J, Drosik K, Dziadziuszko R, Kordek R, Kozielski J, Kowalski D, Krzakowski M, Nikliński J, Olszewski W, Orłowski T, Ramlau R, Roszkowski-Śliż K

Lung cancer is in Poland the most common malignancy. Non-small cell lung cancer (NSCLC) accounts for approximately 80% of all lung tumors. In the multidisciplinary treatment of non-small cell lung cancer patients the role of chemotherapy and, most recently, molecular targeted therapy is increasing. In 2005 we published recommendations for systemic treatment of non-small cell lung cancer and mesothelioma. As many new studies have been published since, it was necessary to update this document. We present here a consensus statement on this topic, prepared by a panel of experts in oncology, thoracic surgery, pathology and pneumonology.



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Mesothelioma Cancer   

Unlike lung cancer, there is no association between mesothelioma and smoking Mesothelioma is a wizardry of cancer that is almost always caused by previous exposure to asbestos Mesothelioma is the word used to describe a cancerous tumor that involves the mesothelial cells of an organ, often the lungs, heart, or abdominal organs. Its greatest easily understood site is the pleura (outer lining of the lungs and chest cavity), but it may also occur in the peritoneum (the lining of the abdominal cavity) or the pericardium (a sac that surrounds the heart).

 Surpassingly people who develop mesothelioma get hold of worked on jobs where they inhaled asbestos particles, or carry been exposed to asbestos dust and fibre in other ways, such as by washing the clothes of a family member who worked with asbestos, or by home renovation using asbestos cement products. It can also occur in children; however, these cases are not thought to be associated with asbestos exposure.

 Symptoms of peritoneal mesothelioma include weight loss and cachexia, abdominal swelling and pain due to ascites (a buildup of fluid in the abdominal cavity).  A history of exposure to asbestos may increase clinical suspicion for mesothelioma. Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, anemia, and fever. Symptoms of mesothelioma may not appear until 20 to 50 years after exposure to asbestos. This is the end of a expertise that usually begins with symptoms that send most people to the doctor: a fluid build-up around the lungs (pleural effusions), shortness of breath, suffering in the chest, or suffering or swelling in the abdomen.

 A physical examination is performed, followed by chest X-ray and often lung function tests. Shortness of breath, cough, and aches and in the chest due to an accumulation of fluid in the pleural space are often symptoms of pleural mesothelioma.

 If the cancer has body beyond the mesothelium to other parts of the spread, symptoms may include aches and, trouble swallowing, or swelling of the neck or make contact with.

Tissue is removed, placed under the microscope, and a pathologist makes a definitive diagnosis, and issues a pathology report. Malignant mesothelioma is a rare type of cancer in which malignant cells are found in the sac lining the chest or abdomen. Extremely malignant mesotheliomas accept complex karyotypes, with extensive aneuploidy and rearrangement of swarms chromosomes. 

 

Most people with malignant mesothelioma require worked on jobs where they breathed asbestos. Exposure to airborne asbestos particles increases one's risk of developing malignant mesothelioma.

 Malignant mesothelioma has a peak incidence 35-45 years after asbestos exposure. Malignant mesothelioma has also been linked to remedial radiation using thorium dioxide and zeolite, a silicate in the soil.

 Malignant mesothelioma is often just called simply Mesothelioma and is a form of lung cancer that is quite rare.

 

Malignant mesothelioma is more explicit in men, with a male-to-female ratio of 3:1. In this disease, malignant cells develop in the mesothelium, a protective lining that covers extremely of the body's internal organs.

 

The be obliged of radiation therapy in pleural mesothelioma has been shown to alleviate aches and in the majority of patients that are treated. But unfortunately, the duration of symptom control is short-lived. Radiation has no effect on survival, but it has caused significant palliation in 50% of patients treated for chest aches and and chest wall metastasis. There are now a number of cancer treatment options open to mesothelioma victims. Extrapleural pneumonectomy for selected victims with very early stage disease may extend recurrence-free survival, but the impact it has on overall survival is unknownat this time.

 

Surgical resection has been relied upon because radiation and chemotherapy set up been ineffective legitimate treatments. The 2 surgical procedures used are pleurectomy with decortication and extrapleural pneumonectomy.

 

 

Fwd: The people's councillor dies



---------- Forwarded message ----------
From: Live Search News: asbestos cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: The people's councillor dies
To: mesothelioma77@gmail.com


Vancouver Sun - Former District of North Vancouver councillor Ernie Crist died on Saturday. He was 79 and had been fighting lung cancer, likely caused by breathing asbestos at the North Vancouver shipyards where he worked for many years. His passing was noted at ...

Wed, 20 Feb 2008 18:54:00 GMT

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Source: http://www.canada.com/vancouversun/news/story.html?id=08c00d93-6042-427c-a35c-388e00b252fd&k=66463
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Fwd: Deciphering hormone therapy: Conventional vs. compounded



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: Deciphering hormone therapy: Conventional vs. compounded
To: mesothelioma77@gmail.com


Q : I've been reading a lot about bioidentical hormones lately. What are they exactly? Are they an improvement on the usual hormone-replacement therapy? A : Bioidentical hormones are chemically identical to ...

Thu, 21 Feb 2008 01:47:19 GMT


Source: http://www.chicagotribune.com/features/lifestyle/q/chi-0224_doc_r_k_dfeb24,1,6053690.story
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Fwd: Legendary N. Van politician dies



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From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: Legendary N. Van politician dies
To: mesothelioma77@gmail.com


Longtime North Vancouver councillor Ernie Crist was recently honoured with the District of North Vancouvers highest hounour, Freedom of the District.

Thu, 21 Feb 2008 01:43:41 GMT


Source: http://www.bclocalnews.com/greater_vancouver/northshoreoutlook/news/15812952.html
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Fwd: HIV/AIDS in Black America: What You Don't Know Can Kill You



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From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: HIV/AIDS in Black America: What You Don't Know Can Kill You
To: mesothelioma77@gmail.com


In March 1981, doctors and pharmacists began discovering a medical phenomenon. Eight young New Yorkers had developed red and purple lesions, which doctors would diagnose as an aggressive form of Kaposi's ...

Thu, 21 Feb 2008 01:56:40 GMT


Source: http://www.seattlemedium.com/news/Article/Article.asp?sID=3&NewsID=86200
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Fwd: Report: Big Tobacco's Guinea Pigs-How an Unregulated Industry...



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: Report: Big Tobacco's Guinea Pigs-How an Unregulated Industry...
To: mesothelioma77@gmail.com


Report: Big Tobacco's Guinea Pigs-How an Unregulated Industry Experiments on America's Kids and Consumers Press release: "An insidious new generation of tobacco products is threatening efforts to reduce tobacco ...

Thu, 21 Feb 2008 02:28:36 GMT


Source: http://www.bespacific.com/mt/archives/017565.html
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Thursday, February 21, 2008

Fwd: Giving Patients a Lift



---------- Forwarded message ----------
From: Live Search News: asbestos cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: Giving Patients a Lift
To: mesothelioma77@gmail.com


Forbes - ... Feb. 20 /PRNewswire/ -- The Mesothelioma Applied Research Foundation (Meso Foundation) has established the Mary and Bob Cosentino Travel Grant Program to help newly-diagnosed patients consult with an expert on this very grave asbestos-related cancer. ...

Wed, 20 Feb 2008 23:19:00 GMT

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Source: http://www.forbes.com/prnewswire/feeds/prnewswire/2008/02/20/prnewswire200802201818PR_NEWS_USPR_____NYW135.html
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Fwd: Study: Night light raises cancer risk



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From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: Study: Night light raises cancer risk
To: mesothelioma77@gmail.com


Exposure to light at night is the most powerful factor in breast cancer besides genetic defects, according to a new University of Haifa study.

Thu, 21 Feb 2008 04:15:07 GMT


Source: http://www.jpost.com/servlet/Satellite?pagename=JPost%2FJPArticle%2FShowFull&cid=1203518556682
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Fwd: Half A Million Cancer Deaths Have Been Averted Since Death Rate Drop, Report Shows



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From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: Half A Million Cancer Deaths Have Been Averted Since Death Rate Drop, Report Shows
To: mesothelioma77@gmail.com


Society epidemiologists predict that in the U.S. in 2008 there will be 1,437,180 new cancer cases and 565,650 cancer deaths .

Thu, 21 Feb 2008 04:21:19 GMT


Source: http://www.sciencedaily.com/releases/2008/02/080220091424.htm
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Fwd: Obituaries in the news



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From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: Obituaries in the news
To: mesothelioma77@gmail.com


Vunies High, the sister of boxing great Joe Louis, was found frozen to death outside her apartment at an assisted-living center, authorities said.

Thu, 21 Feb 2008 04:26:03 GMT


Source: http://www.chron.com/disp/story.mpl/ap/nation/5557653.html
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Fwd: Cannabis: a lung cancer risk



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:15 AM
Subject: Cannabis: a lung cancer risk
To: mesothelioma77@gmail.com


Is smoking cannabis bad for you? Experts are divided on this. On one hand, as far as illicit drugs are concerned, most experts agree that it's far less harmful than heroin and ice.

Thu, 21 Feb 2008 04:47:25 GMT


Source: http://www.abc.net.au/health/thepulse/stories/2008/02/21/2168648.htm
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Fwd: Bayer Schering/Onyx: Nexavar suffers setback in lung cancer (Pharmaceutical Business Review)



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From: Yahoo! News Search Results for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:14 AM
Subject: Bayer Schering/Onyx: Nexavar suffers setback in lung cancer (Pharmaceutical Business Review)
To: mesothelioma77@gmail.com


Disappointing Phase III data presents a considerable blow to Nexavars prospects of expansion into the potentially lucrative indication of non-small-cell lung cancer. While development of the drug is likely to continue in this indication, the negative trial results and inevitable delay to market could prove costly.

Thu, 21 Feb 2008 02:32:16 GMT

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Source: http://us.rd.yahoo.com/dailynews/rss/search/lung+cancer/SIG=13fbccvd0/*http%3A//www.pharmaceutical-business-review.com/article_feature.asp?guid=6F287202-8739-4ABF-8F7F-50DB314E0BA4
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Fwd: Smoking's Effects on Genes May Play a Role in Lung Cancer Development and Survival (National Cancer Institute)



---------- Forwarded message ----------
From: Yahoo! News Search Results for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:14 AM
Subject: Smoking's Effects on Genes May Play a Role in Lung Cancer Development and Survival (National Cancer Institute)
To: mesothelioma77@gmail.com


Smoking plays a role in lung cancer development and now scientists have shown that smoking also affects the way genes are expressed, leading to alterations in cell division and regulation of immune response.

Wed, 20 Feb 2008 16:05:48 GMT

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Source: http://us.rd.yahoo.com/dailynews/rss/search/lung+cancer/SIG=124rj6t1j/*http%3A//www.cancer.gov/newscenter/pressreleases/GenesSmokingLandi
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Fwd: Genzyme Genetics works with British firm on lung cancer diagnostics (bizjournals.com via Yahoo! Finance)



---------- Forwarded message ----------
From: Yahoo! News Search Results for lung cancer <rssfwd@rssfwd.com>
Date: Thu, Feb 21, 2008 at 12:14 AM
Subject: Genzyme Genetics works with British firm on lung cancer diagnostics (bizjournals.com via Yahoo! Finance)
To: mesothelioma77@gmail.com


Genzyme Genetics has signed an agreement with an English company that will bring a series of lung cancer tests to the global marketplace.

Wed, 20 Feb 2008 16:10:16 GMT

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Fwd: Suits to regain 401(k) losses OKd



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Date: Wed, Feb 20, 2008 at 10:56 PM
Subject: Suits to regain 401(k) losses OKd
To: collegeschoolloan@gmail.com


WASHINGTON -- The U.S. Supreme Court ruled today that employees with 401(k) plans can sue to recover losses when their savings are not handled in their best interest, a decision that could spark claims against the retirement system that now predominates

Wed, 20 Feb 2008 21:35:00 GMT

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Fwd: Girlfriend: Shooter was taking 3 prescriptions



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From: Moreover Technologies - Top stories - of 858 returned <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 10:56 PM
Subject: Girlfriend: Shooter was taking 3 prescriptions
To: collegeschoolloan@gmail.com


Steven Kazmierczak had been taking Xanax, Ambien, Prozac, girlfriend says Girlfriend: Psychiatrist prescribed all three medications Boyfriend recently had become secretive about computer, Jessica Baty says Woman denies changing her story or misleading

Wed, 20 Feb 2008 20:04:00 GMT

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Wednesday, February 20, 2008

Fwd: LegalView Mesothelioma Blog Reports That Asbestos Exposure Slows ...



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From: Live Search News: asbestos cancer <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 4:02 AM
Subject: LegalView Mesothelioma Blog Reports That Asbestos Exposure Slows ...
To: mesothelioma77@gmail.com


PR.com - ... mineral was used because of its resistance to heat and fire damage as well as its strength, however, it was discovered that the inhalation of asbestos fibers and dust was highly toxic to individuals and can cause asbestosis and mesothelioma cancer ...

Wed, 20 Feb 2008 07:48:00 GMT

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Fwd: [A Patient with Gastric Cancer Complicated with Multiple Spinal Bone Metastases Showing a Complete Remission to Combination of S-1 and CDDP.]



---------- Forwarded message ----------
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 4:02 AM
Subject: [A Patient with Gastric Cancer Complicated with Multiple Spinal Bone Metastases Showing a Complete Remission to Combination of S-1 and CDDP.]
To: mesothelioma77@gmail.com


[1]Gan To Kagaku Ryoho. 2008 Feb; 35(2): 311-313
Kawano I, Yufu M

The patient was a 66-year-old man. Total gastrectomy was performed due to BorrmannVtype moderately differentiated adenocarcinoma of the middle part of the stomach. The final diagnosis was UM 7x6 cm, sT3, sN1, sH0, sP0, sM0, sCY0, sStage IIIA, PM (-), DM (-), D2+alpha, Cur B, ly2, v2. Because CEA had increased slowly from ten months after the operation, it was judged a possibly partial relapse. Twice-administered CDDP 80 mg/body and S-1 80 mg on the eighth day served to decrease CEA. He was hospitalized again due to fracture of the spine, though he left the hospital once. The patient was diagnosed by MRI inspection of the vertebrae thoracicae and the lumbar vertebra as multiple spinal bone metastases. After CDDP 60 mg/body of day 8 was administered twice at S-1 80 mg/day, CEA became normal. Osteolytic changes of the spinal bone disappeared. The 24 months from February 2004 to January 2006 passed without additional treatment. His CEA value tended to rise within the normal range in February 2006. After that, the CEA level increased with a 4-week cycle of 2 weeks of S-1 40-80 mg alternating with a two-week rest.



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Fwd: [Two Advanced/Recurrent Breast Cancer Cases Effectively Treated by Trastuzumab/Capecitabine Combination Therapy.]



---------- Forwarded message ----------
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Wed, Feb 20, 2008 at 4:02 AM
Subject: [Two Advanced/Recurrent Breast Cancer Cases Effectively Treated by Trastuzumab/Capecitabine Combination Therapy.]
To: mesothelioma77@gmail.com


[1]Gan To Kagaku Ryoho. 2008 Feb; 35(2): 319-322
Inoue S, Inoue M, Takahashi H, Inoue A, Kunitomo K, Fujii H

Trastuzumab/capecitabine combination therapy was performed for two advanced/recurrent breast cancer cases with acute deterioration of the disease. The time until partial response in the first case was 7 months and in the second case 12 months. Adverse events were slight, though a standard dose as a single drug was used for each drug. The treatment time course was shortened because capecitabine was an oral drug. Therefore, this combination therapy was expected to maintain high quality of life and obtain a high response rate.



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Source: http://www.hubmed.org/display.cgi?uids=18281774
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Fwd: Musculoskeletal syndromes associated with malignancy (excluding hypertrophic osteoarthropathy).



---------- Forwarded message ----------
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Feb 20, 2008 4:02 AM
Subject: Musculoskeletal syndromes associated with malignancy (excluding hypertrophic osteoarthropathy).
To: mesothelioma77@gmail.com


[1]Curr Opin Rheumatol. 2008 Jan; 20(1): 100-5
Naschitz JE, Rosner I

PURPOSE OF REVIEW: To examine recent data about the association between rheumatic disorders and cancer. This article focuses on paraneoplastic rheumatic disorders, which usually precede by a short period of time the diagnosis of malignancy, and on malignant transformation, which occurs late in the course of rheumatic disorders. Evidence of causality between malignancies and rheumatic disorders was reviewed based on statistical indicators (standardized incidence ratios and odds ratios) and by applying Bradford Hill's criteria of causality. RECENT FINDINGS: Firm epidemiological evidence was found attesting that dermatomyositis and polymyostis may present as paraneoplastic syndromes. Several other musculoskeletal disorders may be present akin to paraneoplastic syndrome, based on clinicians' impressions, but with scarce epidemiological evidence supporting a causal determinism. In contrast, robust evidence has accumulated on the role of longstanding rheumatoid arthritis, Sjögren's syndrome and systemic sclerosis as premalignant conditions. Evidence that systemic lupus erythematosus may evolve into lymphoma is equivocal. SUMMARY: The link between malignancies and rheumatic disorders may impact on clinical practice. First, paraneoplastic rheumatic syndromes can provide the clinician with hints for earlier diagnosis of occult cancer. Second, the risk of malignant transformation during the course of rheumatic disorders may motivate the search for strategies aimed at prevention.



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Source: http://www.hubmed.org/display.cgi?uids=18281865
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Fwd: The feasibility of online genetic testing for lung cancer susceptibility: uptake of a web-based protocol and decision outcomes.



---------- Forwarded message ----------
From: HubMed - cancer <rssfwd@rssfwd.com>
Date: Feb 20, 2008 4:02 AM
Subject: The feasibility of online genetic testing for lung cancer susceptibility: uptake of a web-based protocol and decision outcomes.
To: mesothelioma77@gmail.com


[1]Genet Med. 2008 Feb; 10(2): 121-130
O'Neill SC, White DB, Sanderson SC, Lipkus IM, Bepler G, Bastian LA, McBride CM

PURPOSE:: To examine the feasibility of offering genetic susceptibility testing for lung cancer (GSTM1) via the Internet to smokers who were blood relatives of patients with lung cancer. Outcomes include proportion who logged on to the study website to consider testing, made informed decisions to log on and to be tested. METHODS:: Baseline measures were assessed via telephone survey. Participants could choose to log on to the study website; those who did were offered testing. Informed decisions to log on and to be tested were indicated by concordance between the decision outcome and test-related attitudes and knowledge. RESULTS:: Three hundred four relatives completed baseline interviews. One hundred sixteen eligible relatives expressed further interest in receiving information via the web. Fifty-eight logged on and 44 tested. Those logging on expressed greater quit motivation, awareness of cancer genetic testing, and were more likely to be daily Internet users than those who did not log on. Approximately half of the sample made informed decisions to log on and to be tested. CONCLUSION:: Interest in a web-based protocol for genetic susceptibility testing was high. Internet-delivered decision support was as likely as other modalities to yield informed decisions. Some subgroups may need additional support to improve their decision outcomes.



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Source: http://www.hubmed.org/display.cgi?uids=18281920
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Fwd: Researchers develop cancer breath test



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 20, 2008 4:02 AM
Subject: Researchers develop cancer breath test
To: mesothelioma77@gmail.com


The test may help doctors detect cancer cells . A new laser analyser might be able to help doctors detect cancer, asthma or other diseases by sampling a patient's breath.

Wed, 20 Feb 2008 04:10:20 GMT


Source: http://www.abc.net.au/news/stories/2008/02/20/2167835.htm
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Fwd: Opportunities in China Lure Scientists Home



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 20, 2008 4:02 AM
Subject: Opportunities in China Lure Scientists Home
To: mesothelioma77@gmail.com


By Ariana Eunjung Cha Washington Post Foreign Service Wednesday, February 20, 2008; Page D01 SHANGHAI -- Sheng Huizhen's life story is typical of immigrants who succeeded in America.

Wed, 20 Feb 2008 04:42:33 GMT


Source: http://www.washingtonpost.com/wp-dyn/content/article/2008/02/19/AR2008021902509.html?nav=rss_world
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Tuesday, February 19, 2008

Fwd: Indoor air quality can be big problem



---------- Forwarded message ----------
From: Live Search News: asbestos cancer <rssfwd@rssfwd.com>
Date: Feb 16, 2008 7:08 PM
Subject: Indoor air quality can be big problem
To: mesothelioma77@gmail.com


Rochester Democrat and Chronicle - Asbestos has potential for lung cancer deaths. ... The exposure can take quite a while," Mazurowski said. Unlike other indoor air quality issues, homeowners are advised not to try to remove asbestos themselves. "You need a professional to remove the ...

Sat, 16 Feb 2008 07:53:00 GMT

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Source: http://www.rochesterdandc.com/apps/pbcs.dll/article?AID=/20080216/LIVING/802160303
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Fwd: Development of new targeted therapies for breast cancer.



---------- Forwarded message ----------
From: HubMed - breast cancer <rssfwd@rssfwd.com>
Date: Feb 16, 2008 7:08 PM
Subject: Development of new targeted therapies for breast cancer.
To: mesothelioma77@gmail.com


[1]Cancer Treat Res. 2008; 141: 119-34
Doyle DM, Miller KD





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Source: http://www.hubmed.org/display.cgi?uids=18274086
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Fwd: Staging the Axilla with selective sentinel node biopsy in patients with previous excision of non-palpable and palpable breast cancer.



---------- Forwarded message ----------
From: HubMed - breast cancer <rssfwd@rssfwd.com>
Date: Feb 16, 2008 7:08 PM
Subject: Staging the Axilla with selective sentinel node biopsy in patients with previous excision of non-palpable and palpable breast cancer.
To: mesothelioma77@gmail.com


[1]Eur J Nucl Med Mol Imaging. 2008 Feb 12;
Ruano R, Ramos M, Garcia-Talavera JR, Serrano E, De Arriba A, Gonzalez-Orus J, Iglesias M, Macias MC

PURPOSE: To present our experience in the therapeutic approach of the sentinel node biopsy (SNB) in patients with previous excision of the breast cancer, divided in non-palpable and palpable lesions, in comparison with time treatment and stagement of breast cancer. METHODS: In the period 2001-2006, 138 patients with prior diagnostic excisional biopsy (96 non-palpable and 42 palpable breast cancer) and 328 without previous surgery (32 non-palpable; 296 palpable cancer) were treated. The combined technique ((99m)Tc-colloidal rhenium and isosulfan blue dye) was the approach for sentinel lymph node (SLN) detection. Axillary lymph node dissection (ALND) was completed only when the SLN was positive for metastasis or not located. RESULTS: Detection rate, if there was prior surgery, was 95% for non-palpable and 98% for palpable cancer, and 99% for one-time treatment group. Metastasis rate in the SLN was 15% in non-palpable cancer (14/91), significantly smaller than in palpable breast cancer (39% if prior surgery and 37% in one-time surgery). According to tumoral size, ALND metastasis rate was similar for T1 and T2 tumors (43-44%). In the follow-up of the groups with prior diagnostic biopsy or surgery of the breast cancer we have not found any false negative in the axilla. CONCLUSION: The detection of the SLN is also feasible in patients with previous surgery of breast cancer. Because SLN metastasis rates are significantly smaller in non-palpable lesions, the effort in screening programs for early detection of breast cancer and also in improving histopathological confirmation of malignancy with ultrasound or stereotactic guided core biopsies must continue.



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Source: http://www.hubmed.org/display.cgi?uids=18274744
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Fwd: Dad takes up cause where son left off



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 18, 2008 9:04 AM
Subject: Dad takes up cause where son left off
To: mesothelioma77@gmail.com


There was one thing Eric Gold was eager to do after getting a double lung transplant in 2004: climb 94 flights of stairs in the John Hancock Center.

Mon, 18 Feb 2008 10:15:41 GMT


Source: http://www.suntimes.com/news/metro/799523,CST-NWS-hustle18.article
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Fwd: Good To Know



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 18, 2008 9:04 AM
Subject: Good To Know
To: mesothelioma77@gmail.com


SS Peter and Paul to hold auction SS Peter and Paul Catholic School will hold its 15th annual auction and dinner dance, "A Night at the Oscars," Saturday at Bobak's Signature Events Center in Woodridge.

Mon, 18 Feb 2008 10:39:21 GMT


Source: http://www.suburbanchicagonews.com/napervillesun/lifestyles/799299,6_5_NA18_GOODTOKNOW_S1.article
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Fwd: Consumer insight



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 18, 2008 9:04 AM
Subject: Consumer insight
To: mesothelioma77@gmail.com


Dangers in your home Test for radon gas, gain peace of mind Jeremy Worley, a certified radon mitigation specialist for Greene's Inc., discusses ways to detect radon gas and measures to address it.

Mon, 18 Feb 2008 10:20:56 GMT


Source: http://www.sltrib.com/ci_8291973
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Fwd: Michael - Mike' M. Wilson



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 18, 2008 9:04 AM
Subject: Michael - Mike' M. Wilson
To: mesothelioma77@gmail.com


Michael "Mike" M. Wilson, of La Mesa, N.M., died Feb. 8 of lung cancer.

Mon, 18 Feb 2008 12:39:46 GMT


Source: http://www.bendbulletin.com/apps/pbcs.dll/article?AID=/20080218/NEWS05/802180314/1001&nav_category=
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Fwd: Late diagnoses tied to lack of insurance



---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 18, 2008 9:04 AM
Subject: Late diagnoses tied to lack of insurance
To: mesothelioma77@gmail.com


By KEVIN SACK A nationwide study has found that uninsured people and those covered by Medicaid are more likely than those with private insurance to receive a diagnosis of cancer in the late stages of the ...

Mon, 18 Feb 2008 13:07:00 GMT


Source: http://www.star-telegram.com/national_news/story/479597.html
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Fwd: Some cancer patients turn to 'coaches'







---------- Forwarded message ----------
From: Search for lung cancer <rssfwd@rssfwd.com>
Date: Feb 18, 2008 9:04 AM
Subject: Some cancer patients turn to 'coaches'
To: mesothelioma77@gmail.com


Last updated: 6:03 a.m., Monday, February 18, 2008 The advice made her head spin: Have the lump removed.

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